Publications

Huijben, S. & Paaijmans, K.P. Putting evolution in elimination: winning our ongoing battle with evolving malaria mosquitoes and parasites. Evolutionary Applications, in press

Huijben, S., Chan, B.H.K., & Read, A.F. (2015). The relevance of undetectably rare resistant malaria parasites in treatment failure: experimental evidence from Plasmodium chabaudi. American Journal of Hygiene and Tropical Medicine 92: 1214-1221.

Birger S., Kouyos R.D., Cohen T., Griffiths E., Huijben S., Mina M., Volkova V., Grenfell B., and Metcalf C.J.E. (2015). The potential impact of coinfection on antimicrobial chemotherapy and drug resistance. Trends in Microbiology 23: 537–544.

Glunt K.D., Abílio A.P., Bassat Q., Bulo H., Gilbert A.E., Huijben S., Manaca M.N., Macete E., Alonso P. & Paaijmans K.P. (2015). Long-lasting insecticidal nets no longer effectively kill the highly resistant Anopheles funestus of southern Mozambique. Malaria Journal 14: 298.

Day, T., Huijben, S., & Read, A.F. (2015). Is selection relevant in the evolutionary emergence of drug resistance? Trends in Microbiology 23: 126-133.

Kouyos, R.D., Metcalf, C.J.E., Birger. R., Klein, E.Y., zur Wiesch, P.A., Ankomah, P., Arinaminpathy, N., Bogich, T.L., Bonhoeffer, S., Brower, C., Chi-Johnston, G., Cohen, E., Day, T., Greenhouse, B., Huijben, S., Metlay, J., Mideo, N., Pollitt, L.C., Read, A.F., Smith, D.L., Standley, C., Wale, N., & Grenfell, B. (2014). The path of least resistance: aggressive or moderate treatment. Proceedings of the Royal Society of London Series B. 281: 20140566.

Pollitt, L.C., Huijben, S., Sim, D.G., Salathe, R.M., Jones, M. & Read, A.F. (2014). Rapid response to selection, competitive release and increased transmission potential of artesunate-selected Plasmodium chabaudi malaria parasites. PLoS Pathogens 10: e1004019.

Vanaerschot, M., Huijben, S., Van den Broeck, F., Dujardin, J-C. (2014). Drug resistance in vector-borne parasites: multiple actors and scenarios for an evolutionary arms race. FEMS Microbiology Reviews 38: 41-55.

Huijben, S., Bell, A.S., Sim, D.G., Salathe, R., Tomasello, D., Mideo, N., Day, T., & Read, A.F. (2013). Aggressive chemotherapy and the selection of drug resistant pathogens. PLoS Pathogens 9: e1003578.

Bell, A.S, Huijben, S., Paaijmans, K.P., Sim, D., Chan, B.H.K., Nelson, W.A., & Read A.F. (2012). Enhanced transmission of drug-resistance parasites to mosquitoes following drug treatment in rodent malaria. PLoS One 7: e37172.

Huijben, S., Sim, D., Nelson, W.A., & Read, A.F. (2011), The fitness of drug resistant malaria parasites in a rodent model: multiplicity of infection. Journal of Evolutionary Biology 24: 2410-2422.

Metcalf, C.J.E., Graham, A.L., Huijben, S., Barclay, V.C., Long, G.H., Grenfell, B.T., Read, A.F., & Bjornstad, O.N. (2011)  Partitioning and quantifying regulatory mechanisms acting on within host malaria using the effective propagation number. Science 333: 984-988.

Read, A.F., Day, T., & Huijben, S. (2011). The evolution of drug resistance and the curious orthodoxy of aggressive chemotherapy. PNAS 108: 10871-10877.

Huijben, S., Nelson, W.A., Wargo, A.R., Sim, D.G., Drew, D.R., & Read, A.F. (2010). Chemotherapy, within-host ecology and the fitness of drug resistant malaria parasites. Evolution 64: 2952-2968.

KP Paaijmans, S Huijben, AK Githeko & W Takken. (2009). Competitive interactions between larvae of the malaria mosquitoes Anopheles arabiensis and Anopheles gambiae under semi-field conditions in western Kenya. Acta Tropica 109: 124-130.

Read, A.F. & Huijben, S. (2009). Evolutionary biology and the avoidance of antimicrobial resistance. Evolutionary Applications 2: 40-51.

Huijben, S., Schaftenaar,W., Wijsman,A., Paaijmans, K. & Takken, W. (2007). Avian malaria in Europe: an emerging infectious disease? In: Emerging pests and vector-borne diseases in Europe. Takken W. & Knols B.G.J, editors. Wageningen Academic Publishers, Wageningen.

Takken, W., van Rooij, E.M.A., Verhulst, N.O., Jacobs, F., Huijben, S., Beeuwkes, J., Groot, N ., Vos, J Spitzen, V.C.A ., Heutink, R.C.G. & van Rijn, P.A. (2007). Bluetongue: an emerging vector-borne disease outbreak in North-western Europe. In: Emerging pests and vector-borne diseases in Europe. Takken, W. & Knols, B.G.J, editors. Wageningen Academic Publishers, Wageningen.

Wargo, A. R., Huijben, S., de Roode, J.C., Shepard, J., & Read, A.F. (2007). Competitive release and facilitation of drug resistant parasites following therapeutic chemotherapy in a rodent malaria model. Proceedings of the National Academy of Science USA 104: 19914-19919.

Wargo A. R., De Roode J. C., Huijben S., Drew D. R., Read A. F. (2007). Transmission stage investment of malaria parasites in response to in-host competition. Proceedings of the Royal Society of London Series B. 274: 2759-2768.

de Roode, J.C., Pansini, R., Cheesman, S.J., Helinski, M.E.H., Huijben, S., Wargo, A.R., Bell, A.S., Chan, B.H.K ., Walliker, D., & Read, A.F. (2005). Virulence and competitive ability in genetically diverse malaria infections. Proceedings of the National Academy of Sciences USA 102: 7624-7628.